ecteinascidin 743

RN = 114899-77-3
SY = ET 743
SY = ET-743
SY = trabectedin
SY = NSC 684766
SY = Yondelis
HM = *Dioxoles
HM = *Isoquinolines
SO = Br J Cancer 1996 Apr;73(8):875-83
PA = Antineoplastic Agents, Alkylating
FR = 106
NO = a complex structure that includes isoquinolines joined by a cyclic ester; Guanine N2 alkylator with potent antiproliferative activity; a marine natural product from Ecteinascidia turbinata; ecteinascidin-729 is a metabolite; cells induced to tolerance for this have defective XP6 protein
DA = 19960603
MR = 20031022
UI = C099150

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